Scientists find a brain circuit that indicates when to stop eating; would help fight obesity

THURSDAY, JUNE 10TH, 2021

The activation of this circuit produces a remarkable weight loss effect.

🖊Sciences Advances 📸DAVID MALAN/GETTY IMAGES


Researchers at Baylor University school of medicine, in the United States, have discovered the brain circuit that indicates when to stop eating; getting it regulated will allow to combat.

The team of Doctors Qi Wu and Yong Han discovered a new circuit that connects a unique subset of dopamine-producing neurons with the posterior neurons of the rhogbencephalon (lower part of the brainstem) and that potently suppresses food intake causing satiety in mice.

They also found that the FDA-approved drug methylphenidate produces a remarkable weight loss effect by activating this circuit, opening the possibility that regulation of this circuit can help people control their weight.

Using several advanced techniques to study neuronal function, such as cell-specific circuit mapping, optogenetics, and real-time recordings of brain activity, researchers discovered a novel neural circuit that connects a unique group of dopamine-producing neurons called DA-VTA with later-target neurons known as DRD1-LPBN and that regulates food consumption in mice.

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